Aug 26, 2010 - Study to Evaluate Effect on Sleep/Wake Cycle in Blind Individuals with Non-24-Hour Sleep Wake Disorder - Vanda Pharmaceuticals Inc. (Nasdaq: VNDA), announced it has initiated a Phase III clinical trial to evaluate tasimelteon in patients with Non-24-Hour Sleep Wake Disorder (N24HSWD), a condition experienced primarily by totally blind individuals that results in abnormal night sleep patterns and chronic daytime sleepiness. Tasimelteon binds to high affinity melatonin receptors located in the brain that are believed to regulate circadian rhythms, or sleep/wake cycles."Blind individuals with no light perception do not receive external light and darkness signals that synchronize our internal body clocks... Vanda Pharmaceuticals' Press Release -
